Magnesium sulfate
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Magnesium sulfate is a magnesium salt having sulfate as the counterion. It has a role as an anticonvulsant, a cardiovascular drug, a calcium channel blocker, an anaesthetic, a tocolytic agent, an anti-arrhythmia drug and an analgesic. It is a magnesium salt and a metal sulfate.
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
Magnesium sulfate must be used with caution in patients suspected of or known to have renal Red.
Magnesium sulfate should not be used in hepatic coma if there is a risk of renal failure.
Parenteral magnesium salts should be used with caution in patients with myasthenia gravis.
Serum calcium levels should be routinely monitored in patients receiving magnesium sulfate.
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